Colorectal Cancer (Colon Cancer)

What is Colorectal Cancer?

As the name indicates, Colorectal or colon cancer starts in the colon or rectum. These organs constitute the lower portion of the human digestive system. A colon is also referred to as the large intestine, and the rectum is situated at the end of the colon. According to research, nearly 1 out of 22 men and 1 out of 24 women suffer from colorectal cancer. To define the criticalness of cancer, stages are defined for it ranging from Stage 1 which is the earliest stage and less critical to Stage 4 which is the most advanced stage. Let’s know each of them in detail:

1st Stage Colon cancer:

In this, cancer penetrates the lining of the colon or rectum and is limited to only this organ and has not spread to walls of it.

2nd Stage Colon cancer:

Cancer spread to the colon walls but don’t affect nearby tissues and lymph nodes.

3rd Stage Colon cancer:

In this stage, cancer spreads to the regional lymph nodes and may involve nearby organs but not to other body parts.

4th Stage Colon cancer:

Cancer gets spread to the non-regional lymph nodes and distant organs of the body.

Symptoms

You may not experience the symptoms of colorectal cancer in the starting stage. However, some people might experience symptoms like:

  • Long-standing diarrhea or constipation.
  • Stool color will get changed along with the consistency.
  • Blood in stool.
  • Abdominal cramps and pain.
  • Excessive gas.

Testing Options For Colorectal Cancer Screening

Several test options are available for colorectal cancer screening:

Stool-based tests like-
  • Highly sensitive fecal immunochemical test (FIT) every year
  • Highly sensitive guaiac-based fecal occult blood test (gFOBT) every year
  • Multi-targeted stool DNA test (MT-sDNA) every 3 years

Visual (structural) exams of the colon and rectum like-
  • CT colonography (virtual colonoscopy) every 5 years
  • Flexible sigmoidoscopy (FSIG) every 5 years

Treatment:

Colon Cancer:

  • Stage 1 Colon cancer: surgery only
  • Stage 2 Colon cancer: surgery only and sometimes chemotherapy is also given after surgery
  • Stage 3 Colon cancer: surgery followed by Chemotherapy
  • Stage 4 Colon cancer: Chemotherapy + Targeted therapy, Immunotherapy. sometimes surgery is also done

Rectal Cancer::

  • Stage 1 Rectal Cancer: surgery only
  • Stage 2 Rectal Cancer: surgery only and sometimes chemotherapy is also given after surgery
  • Stage 3 Rectal Cancer: Radiotherapy + surgery + Chemotherapy
  • Stage 4 Rectal Cancer: Chemotherapy +Targeted therapy, Immunotherapy. sometimes surgery is also done